MOTS-c 10mg

Description

Every MOTS-c 10mg vial at Prime Peptides holds 10mg of MOTS-c, packed as freeze-dried powder. In short, it’s a mitochondrial-derived peptide. It’s sold for laboratory research only.

Background on MOTS-c

MOTS-c is a 16-amino-acid peptide coded not in the cell nucleus but in mitochondrial DNA, inside the gene for the 12S ribosomal RNA. Changhan Lee and colleagues in Pinchas Cohen’s lab at the University of Southern California described it in 2015.

It belongs to a small group of mitochondrial-derived peptides, alongside humanin, that act as signals from the mitochondria to the rest of the cell and body.

How MOTS-c works

Most proteins are coded in the cell nucleus. MOTS-c is one of a handful of peptides coded in mitochondrial DNA instead. Its main target looks like the folate cycle, which feeds into AMPK activation and better glucose handling in muscle.

Under stress it can move into the nucleus and change gene expression. Circulating levels drop with age in both mice and people, which is why it’s studied in metabolism and aging.

MOTS-c 10mg product details

• Compound: MOTS-c
• CAS number: 1627580-64-6
• Molecular formula: C101H152N28O22S2
• Molecular weight: 2,174.6 g/mol
• Structure: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: Prime, For Research Only, Lyophilized Powder
• SKU: PRIME-MOTSC-10
• Intended use: laboratory research only

What the literature says about MOTS-c

The 2015 Cell Metabolism paper reported that MOTS-c prevented diet-induced obesity and insulin resistance in mice, working mainly through skeletal muscle.

Reynolds and colleagues reported in Nature Communications in 2021 that exercise raises MOTS-c levels in people, and that treating older mice with it improved their physical performance.

Every study mentioned here is indexed on PubMed, the free database run by the NIH. Try this MOTS-c search.

MOTS-c compared with similar compounds

MOTS-c is a short peptide coded in mitochondrial DNA and linked to AMPK. Here’s how the nearest options in our range differ:

• Retatrutide activates three receptors at once: GIP, GLP-1 and glucagon
• Tirzepatide activates two incretin receptors, GIP and GLP-1
• Semaglutide activates the GLP-1 receptor only and lasts about a week, which makes it the most studied compound in the group
• Eloralintide is a newer long-acting amylin receptor agonist from Lilly, studied for appetite and gastric emptying
• AOD-9604 is a modified 176-191 fragment of growth hormone, studied for fat breakdown without GH’s growth effects

Each one approaches metabolism from a different side: gut hormone receptors, amylin, a growth hormone fragment or the mitochondria. Compare them in our weight loss peptides.

Reconstituting MOTS-c 10mg

There are 10mg of freeze-dried powder in the vial. Divide that by the volume of diluent you add and you have the concentration. For example:

• 1mL of diluent gives 10mg per mL
• 2mL of diluent gives 5mg per mL
• 3mL of diluent gives 3.333mg per mL

Let the vial reach room temperature, swab the stopper with alcohol and let the diluent run slowly down the inside of the glass. Swirl gently until the solution is clear. Shaking creates foam and can damage the peptide. Prime stocks bacteriostatic water for exactly this step.

Keeping MOTS-c 10mg fresh

An easy rule for MOTS-c 10mg: powder in the freezer, solution in the fridge. Light and moisture are what degrade freeze-dried peptides, so leave the vial in its carton.

Let a frozen vial warm up before opening it, since cold glass pulls moisture out of the air.

MOTS-c 10mg quality and verification

The Prime vial label is kept clean: the Prime wordmark, the compound name, “For Research Only” and “Lyophilized Powder”. Keep your order confirmation with your lab records, since it lists exactly what was shipped.

Independent verification usually means HPLC for purity plus mass spectrometry for identity. One without the other only tells half the story.

Write the order number and the date opened on every vial. If a result looks unusual later, you can trace it back to one delivery.

Related to MOTS-c 10mg

• GHK-Cu Copper Peptide 100mg, a copper peptide
• Glutathione 1500mg, an antioxidant tripeptide
• NAD+ 1000mg, a coenzyme
• AOD-9604 5mg, an hGH fragment
• Tirzepatide Peptide, a GIP/GLP-1 agonist

Browse the complete list in our anti-aging peptides and weight loss peptides, or head back to the Prime Peptides home page to see every category.

MOTS-c 10mg FAQ

How much is in each MOTS-c 10mg vial?

10mg of freeze-dried powder per vial.

What do I mix MOTS-c 10mg with?

Most labs use our bacteriostatic water. The mixing guide on this page lists the strength you get from each volume.

How should MOTS-c 10mg be stored?

Freeze the sealed vial at -20°C. After mixing, move it to the fridge at 2 to 8°C and finish it inside roughly 28 days.

Can MOTS-c be used in people or animals?

No. Prime Peptides sells it for laboratory research only. It isn’t approved for human or veterinary use.

Is MOTS-c 10mg in stock?

Yes, it’s in stock now, and shipping is free.

Get MOTS-c 10mg from Prime Peptides

MOTS-c 10mg is in stock at $60.00 per vial, with free shipping. Add it to your cart and check out in a minute. Pay with crypto and you save 15%.

Building a bigger order? See our anti-aging peptides and weight loss peptides.

Prime Peptides sells this product for in-vitro and laboratory research only. It isn’t a medicine, food or dietary supplement, and it can’t be given to people or animals. The FDA has not evaluated any statement on this page. Buyers must be 21 or older and qualified to handle research chemicals.